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KMID : 1035620130010040357
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Allergy Asthma & Respiratory Disease
2013 Volume.1 No. 4 p.357 ~ p.361
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Factors associated with various clinical manifestations of Mycoplasma pneumonia in children
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Kim Yoo-Na
Park Chul-Hyue
Kim Su-Hee
Kim Hyo-Bin
Yoo Soo-Jin
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Abstract
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Purpose: Mycoplasma pneumonia (MP) is a major cause of community-acquired pneumonia in children and young adults. We aimed to investigate the factors that may influence on the clinical manifestations of MP in children.
Methods: A total of 109 admitted children from October 2011 to February 2012 were prospectively enrolled with physical examination and laboratory tests (complete blood count, C-reactive protein [CRP], and particle agglutinin assay). The diagnosis of MP was made when there was an infiltration on the chest X-ray and the particle agglutination test was once over 1:640 or showed 4-fold increase in serial tests. They were grouped by age, fever duration after treatment, presence of pleural effusion and wheezing.
Results: Preschool children showed shorter duration of fever (P=0.001), more wheezing (P<0.001), lower segmented neutrophil (P<0.001), and lower CRP levels (P=0.004) compared to schoolchildren. Prolonged fever (>3 days) and pleural effusion were developed in children with higher CRP (P=0.018 and P=0.007). Wheezing has been developed in children with younger age (P=0.007).
Conclusion: Younger age was a risk factor to develop wheezing in MP and prolonged fever and pleural effusion were more likely to develop in children with higher CRP.
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KEYWORD
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Mycoplasma pneumonia, Age factors, Fever, Pleural effusion, Wheezing, C-reactive protein
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